Tyrphostin
- Where
- 45-1 Ramsey Road, Shirley, NY 11967, USA, San Juan Bautista , CA
- Call
- +1 6316197922
- Contact
- Web
- Tyrphostin Website
- Tags
- Health & Wellness
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About
Tyrphostin AG1024 can inhibit IGF-1R with IC50 of around 400 nM. By inhibiting insulin-like growth factor 1 receptor and insulin receptor, Tyrphostin AG1024 arrested melanoma cell growth. Tyrphostin AG1024 inhibited the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway and restored pRb tumor suppressive function.
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