Terlipressin Acetate

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Terlipressin Acetate
CAT#:  10-101-38
CAS No.: 14636-12-5
Sequence:  H-Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 acetate salt (Disulfide bond)
M.W/Mr.:  1227.4
Molecular Formula:  C52H74N16O15S2
Source:  Synthetic


Description:  Terlipressin is a synthetic analog of vasopressin and is used as a vasoactive drug in the management of hypotension. It is a prodrug, which is converted to (Lys8)- vasopressin after removal of the N-terminal triglycine in vivo. Terlipressin has a longer duration of action and a better safety profile than the parent compound.


Application: Terlipressin has been used as a vasoactive drug in the management of low blood pressure. It also indicates to be used in norepinephrine-resistant septic shock and hepatorenal syndrome. In addition, it is used to treat bleeding esophageal varices.


Areas of Interest: Vasoactive drug

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